Objective: To probe into the current status and quality evaluation of the treatment guidelines for pediatric epilepsy at homeand abroad

so as to provide reference for optimizing clinical guidelines. Methods: PubMed

MedLine

EMBase

CNKI

Wanfang and other databases were retrieved to collect treatment guidelines of pediatric epilepsy. Methodological quality of guidelines was evaluated according to the appraisal of guidelines for research and evaluation Ⅱ (AGREEⅡ). The evaluation system included scope and purpose

stakeholders’ involvement

rigor of development

clarity of presentation

applicability and independence. The main recommended contents were compared and analyzed. Results: Most guidelines referred to first-line and second-line medications and add-on treatments for different epilepsy types and pediatric epilepsy syndromes. The guidelines of the American Epilepsy Society

National Institute for Health and Clinical Excellence

Scottish Interuniversity Guideline Network

International League Against Epilepsy

and American Academy of Neurology were of high quality and strongly recommended. Conclusion: The quality of included guidelines is relatively high

yet further optimization is needed.